| Ecosystem | Type | Status | Ref. |
|---|---|---|---|
| Chesapeake Bay | Sea/Bay/Gulf | Native | 93252 |
| Great Lakes | Lake | native | 5723 |
| Mississippi River | River (basin) | native | 5723 |
| Missouri River | River (basin) | native | 78789 |
| Nearctic | Zoogeographic realm | endemic | 5723 |
| Red River of the North | River (basin) | native | 5723 |
| Rio Grande | River (basin) | extirpated | 78807 |
| Waccamaw | Lake | native | 35360 |